La ingesta de cafeína materna durante el embarazo se asocia con el peso al nacer pero no con la longitud


El objetivo de este estudio es investigar la asociación entre el consumo materno de cafeína y diferentes ocurrencias como la duración gestacional, el peso al nacer y el riesgo de presentar bajo peso al nacer (BPN). Se incluyeron 59.123 mujeres con embarazos sin complicaciones y partos únicos. El consumo de cafeína de diferentes alimentos fue reportado en las semanas gestacionales 17, 22 y 30. La principal fuente de cafeína fue el café. Únicamente la cafeína proveniente del café estuvo asociada con gestación prolongada (8h/100mg/día, P < 0,0000001). Ni la cafeína total, ni la cafeína del café estuvieron asociadas al riesgo de parto pretermino. El consumo de cafeína de diferentes fuentes medida a repetición durante el embarazo, estuvo asociado con menor peso al nacer (P < 0,0000000001). El consumo de cafeína de 200 a 300 mg/día incrementó las probabilidades de BPN (P< 0,00005), comparado con 0 a 50 mg/día. Estos hallazgos tienen implicaciones clínicas incluso para consumos de cafeína menores al máximo recomendado (200mg/día en los países nórdicos y EEUU, 300mg/día de acuerdo a la OMS), el cual estuvo asociado a un aumento del riesgo de presentar BPN.

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