Interacciones género y dósis dependientes entre el consumo de café y la actividad GGT en consumidores de alcohol


Para explorar el papel del café como factor protector de la enfermedad hepática de origen alcohólico, los investigadores del estudio recolectaron información de cerca de 20.000 personas sobre su consumo de café, alcohol y sus niveles séricos de gamma glutamil transpeptidasa (GGT). De la población a estudio, el 89,8 % reportaron diferentes grados de consumo de café. En los hombres, la elevación de la GGT inducida por la ingesta pesada de alcohol (más de 280 gramos al día) se redujo significativamente por el consumo de más de cuatro tazas de café al día. Los resultados del estudio evidenciaron que el café modula el efecto del etanol sobre la GGT sérica, dependiendo de la dosis y del género del paciente.

Danielsson J, Kangastupa P, Laatikainen T, Aalto M, Niemelä O. Dose- and Gender-dependent Interactions between Coffee Consumption and Serum GGT Activity in Alcohol Consumers. Alcohol and Alcoholism Vol. 48, No. 3, pp. 303–307, 2013.

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