Estudio sobre el café y su incidencia en el riesgo de cáncer de próstata y mortalidad por cáncer de próstata en Suecia


Varios estudios epidemiológicos han vinculado el consumo de café con una disminución significativa del riesgo de padecer cáncer de próstata avanzado y letal. El objetivo de este trabajo es explorar la asociación entre el consumo de café y el riesgo de cáncer de próstata mediante un estudio de casos y controles en el marco de la investigación Cancer of the Prostate in Sweden. Se reclutaron 1499 casos y 1112 controles. Se estudió el riesgo general para cáncer de próstata así como el riesgo de cáncer letal, avanzado, localizado, de alto grado, grado 7 y de bajo grado. El consumo de café no resultó asociado con el riesgo general de cáncer de próstata. El riesgo de cáncer de próstata fatal mostró una relación inversa aunque no estadísticamente significativa, para hombres que consumen >5 tazas de café al día (OR=0,64, 95%IC 0,34-1,19 tendencia de p= 0,81). El consumo más alto de café estuvo asociado con un menor riesgo de enfermedad avanzada, sin embargo esta relación no fue estadísticamente significativa (OR= 0,73, 95%IC 0,41-1,30 tendencia de p=0,98). También una asociación no significativa entre el consumo más alto de café y un menor riesgo de cáncer de alto grado (OR= 0,5, 95% IC 26-0.98, tendencia p= 0,13). El riesgo de cáncer localizado, de grado 7, y de bajo grado no resultaron asociados al consumo de café. Este estudio contribuye con alguna evidencia a una asociación inversa entre el consumo de café y el cáncer de próstata de alto grado y letal.

Kathryn M. Wilson, Katarina Bälter, Elisabeth Möller, Hans-Olov Adami, Ove Andrén, Swen-Olof Andersson, Henrik Grönberg, Lorelei A. Mucci. Coffee and risk of prostate cancer incidence and mortality in the Cancer of the Prostate in Sweden Study. August 2013, Volume 24, Issue 8, pp 1575-1581, DOI 10.1007/s10552-013-0234-9, Online ISSN 1573-7225.

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