Correlación inversa entre consumo de café y prevalencia de síndrome metabólico
28-04-2017
Objetivo: Estudiar la asociación entre el consumo de café y té verde y la prevalencia de síndrome metabólico, definido por los criterios del National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) y Japan Society for the Study of Obesity (JASSO). Metodología: Estudio de corte transversal. La población a estudio consistió de 577 hombres y mujeres entre los 35 y 70 años de edad que asistieron a un centro de salud para chequeo médico y eran participantes del estudio Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Se aplicó un cuestionario autodiligenciado que indagó por enfermedad actual y pasada, hábitos de actividad física, frecuencia de consumo de alimentos y bebidas, tabaquismo y consumo de alcohol. Se tomaron datos antoprométricos, tensión arterial, glicemia en ayunas, nivles de triglicéridos y colesterol HDL. El diagnóstico de síndrome metabólico se realizó usando los criterios del NCEP ATP III y JASSO. La asociación entre consumo de café y té verde con la prevalencia de síndrome metabólico se examinó mediante análisis de regresión logística después de ajustar por sexo, edad, consumo energético diario, actividad física, tabaquismo y consumo de alcohol. Se calcularon valores de p, razones de probabilidad (OR) e intervalos de confianza del 95%. Resultados: Se encontró que el consumo de café se asoció significativamente con una menor prevalencia de síndrome metabólico (P de tendencia = 0.03). , a partir del diagnóstico con los criterios del NCEP ATP III. El OR para niveles altos de triglicéridos fue menor en los participantes con un consumo mayor a tres tazas diarias de café ( 150 mg/dl; OR = 0.53, 95% CI 0.31–0.90). En el análisis multivariado, el consumo moderado de café (1.5 a menos de tres tazas al día) se asoció significativamente con mejor prevalencia de síndrome metabólico (OR = 0.52, 95% CI 0.27–0.97) a partir del diagnóstico con los criterios del JASSO. El consumo moderado de café también se asoció a un menor OR para niveles de glicemia elevados (OR = 0.51, 95% CI 0.28–0.93). Por su parte, no se encontró asociación entre el consumo de té verde y la prevalencia de síndrome metabólico. Conclusiones: Este estudio mostró una relación inversa entre el consumo de café y la prevalencia de síndrome metabólico cuando los criterios del NCEP ATP III se usaron para el diagnóstico, principalmente por una prevalencia menor de hipertrigliceridemia.
Takami H, Nakamoto M, Uemura H, Katsuura S, Yamaguchi M, Hiyoshi M, Sawachika F, Juta T, Arisawa K. Inverse correlation between coffee consumption and prevalence of metabolic syndrome: baseline survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan. J Epidemiol. 2013;23(1):12-20
1. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al; American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112:2735–52.
2. Sattar N, Gaw A, Scherbakova O, Ford I, O’Reilly DS, Haffner SM, et al. Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation. 2003;108:414–9.
3. Doi Y, Ninomiya T, Hata J, Yonemoto K, Arima H, Kubo M, et al. Proposed criteria for metabolic syndrome in Japanese based on prospective evidence The Hisayama Study. Stroke. 2009;40:1187–94.
4. Mukai N, Doi Y, Ninomiya T, Hata J, Yonemoto K, Iwase M, et al. Impact of metabolic syndrome compared with impaired fasting glucose on the development of type 2 diabetes in a general Japanese population: the Hisayama study. Diabetes Care. 2009;32:2288–93.
5. Ministry of Health, Labor and Welfare of Japan. A summary of the National Nutritional and Health Survey of 2008. http://www.mhlw.go.jp/houdou/2009/11/h1109-1.html.
6. Alberti KG, Zimmet P, Shaw J. Metabolic syndrome—a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med. 2006;23:469–80.
7. Matsuzawa Y. Metabolic syndrome—definition and diagnostic criteria in Japan. J Atheroscler Thromb. 2005;12:301.
8. Lutsey PL, Steffen LM, Stevens J. Dietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities study. Circulation. 2008;117:754–61.
9. Millen BE, Pencina MJ, Kimokoti RW, Zhu L, Meigs JB, Ordovas JM, et al. Nutritional risk and the metabolic syndrome in women: opportunities for preventive intervention from the Framingham Nutrition Study. Am J Clin Nutr. 2006;84:434–41.
10. Wilsgaard T, Jacobsen BK. Lifestyle factors and incident metabolic syndrome: The Tromsø Study 1979–2001. Diabetes Res Clin Pract. 2007;78:217–24.
11. Deshmukh-Taskar PR, O’Neil CE, Nicklas TA, Yang SJ, Liu Y, Gustat J, et al. Dietary patterns associated with metabolic syndrome, sociodemographic and lifestyle factors in young adults: the Bogalusa Heart Study. Public Health Nutr. 2009;12:2493–503.
12. Ilanne-Parikka P, Laaksonen DE, Eriksson JG, Lakka TA, Lindström J, Peltonen M, et al; Finnish Diabetes Prevention Study Group. Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study. Diabetes Care. 2010;33:1610–7.
13. van Dam RM, Hu FB. Coffee consumption and risk of type 2 diabetes: a systematic review. JAMA. 2005;294:97–104.
14. Huxley R, Lee CM, Barzi F, Timmermeister L, Czernichow S, Perkovic V, et al. Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis. Arch Intern Med. 2009;169:2053–63.
15. Hino A, Adachi H, Enomoto M, Furuki K, Shigetoh Y, Ohtsuka M, et al. Habitual coffee but not green tea consumption is inversely associated with metabolic syndrome: An epidemiological study in a general Japanese population. Diabetes Res Clin Pract. 2007;76:383–9.
16. Matsuura H, Mure K, Nishio N, Kitano N, Nagai N, Takeshita T. Relationship between coffee consumption and prevalence of metabolic syndrome among Japanese civil servants. J Epidemiol. 2012;22:160–6.
17. Balk L, Hoekstra T, Twisk J. Relationship between long-term coffee consumption and components of the metabolic syndrome: the Amsterdam Growth and Health Longitudinal Study. Eur J Epidemiol. 2009;24:203–9.
18. Nagao T, Hase T, Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring). 2007;15:1473–83.
19. Imai K, Nakachi K. Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases. BMJ. 1995;310:693–6.
20. Yang YC, Lu FH, Wu JS, Wu CH, Chang CJ. The protective effect of habitual tea consumption on hypertension. Arch Intern Med. 2004;164:1534–40.
21. Iso H, Date C, Wakai K, Fukui M, Tamakoshi A; JACC Study Group. The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults. Ann Intern Med. 2006;144:554–62.
22. Hamajima N; J-MICC Study Group. The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) to detect gene-environment interactions for cancer. Asian Pac J Cancer Prev. 2007;8:317–23.
23. Tokudome Y, Goto C, Imaeda N, Hasegawa T, Kato R, Hirose K, et al. Relative validity of a short food frequency questionnaire for assessing nutrient intake versus three-day weighed diet records in middle-aged Japanese. J Epidemiol. 2005;15:135–45.
24. SAS Institute. SAS/STAT Software: Changes and Enhancements through Release 6.12, SAS Institute, Cary, NC, 1997.
25. Miyake Y, Kono S, Nishiwaki M, Hamada H, Nishikawa H, Koga H, et al. Relationship of coffee consumption with serum lipids and lipoproteins in Japanese men. Ann Epidemiol. 1999;9:121–6.
26. Nakanishi N, Tatara K, Nakamura K, Suzuki K. Association of lifestyle with serum lipid levels: a study of middle-aged Japanese men. J Epidemiol. 2000;10:216–25.
27. Du Y, Melchert HU, Knopf H, Braemer-Hauth M, Gerding B, Pabel E. Association of serum caffeine concentrations with blood lipids in caffeine-drug users and nonusers—results of German National Health Surveys from 1984 to 1999. Eur J Epidemiol. 2005;20:311–6.
28. Urgert R, Meyboom S, Kuilman M, Rexwinkel H, Vissers MN, Klerk M, et al. Comparison of effect of cafetière and filtered coffee on serum concentrations of liver aminotransferases and lipids: six month randomized controlled trial. BMJ. 1996;313:1362–6.
29. van Rooij J, van der Stegen GH, Schoemaker RC, Kroon C, Burggraaf J, Hollaar L, et al. A placebo-controlled parallel study of the effect of two types of coffee oil on serum lipids and transaminases: identification of chemical substances involved in the cholesterol-raising effect of coffee. Am J Clin Nutr. 1995;61:1277–83.
30. Fried RE, Levine DM, Kwiterovich PO, Diamond EL, Wilder LB, Moy TF, et al. The effect of filtered-coffee consumption on plasma lipid levels. Results of a randomized clinical trial. JAMA. 1992;267:811–5.
31. Kempf K, Herder C, Erlund I, Kolb H, Martin S, Carstensen M, et al. Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial. Am J Clin Nutr. 2010;91:950–7.
32. Lopez-Garcia E, van Dam RM, Willett WC, Rimm EB, Manson JE, Stampfer MJ, et al. Coffee consumption and coronary heart disease in men and women: a prospective cohort study. Circulation. 2006;113:2045–53.
33. Van Dam RM. Coffee consumption and type 2 diabetes: from beans to beta-cells. Nutr Metab Cardiovasc Dis. 2006;16:69–77.
34. Wakabayashi K, Kono S, Shinchi K, Honjo S, Todoroki I, Sakurai Y, et al. Habitual coffee consumption and blood pressure: A study of self-defense officials in Japan. Eur J Epidemiol. 1998;14:669–73.
35. Funatsu K, Yamashita T, Nakamura H. Effect of coffee intake on blood pressure in male habitual alcohol drinkers. Hypertens Res. 2005;28:521–7.
36. Winkelmayer WC, Stampfer MJ, Willett WC, Curhan GC. Habitual caffeine intake and the risk of hypertension in women. JAMA. 2005;294:2330–5.
37. Zhang Z, Hu G, Caballero B, Appel L, Chen L. Habitual coffee consumption and risk of hypertension: a systematic review and meta-analysis of prospective observational studies. Am J Clin Nutr. 2011;93:1212–9.
38. Mesas AE, Leon-Muñoz LM, Rodriguez-Artalejo F, Lopez-Garcia E. The effect of coffee on blood pressure and cardiovascular disease in hypertensive individuals: a systematic review and meta-analysis. Am J Clin Nutr. 2011;94:1113–26.
39. Zhang Y, Lee ET, Cowan LD, Fabsitz RR, Howard BV. Coffee consumption and the incidence of type 2 diabetes in men and women with normal glucose tolerance: the Strong Heart Study. Nutr Metab Cardiovasc Dis. 2011;21:418–23.
40. Lopez-Garcia E, van Dam RM, Rajpathak S, Willett WC, Manson JE, Hu FB. Changes in caffeine intake and long-term weight change in men and women. Am J Clin Nutr. 2006;83:674–80.
41. Murase T, Misawa K, Minegishi Y, Aoki M, Ominami H, Suzuki Y, et al. Coffee polyphenols suppress diet-induced body fat accumulation by down regulating SREBP-1c and related molecules in C57BL/6J mice. Am J Physiol Endocrinol Metab. 2011;300:E122–33.
42. Bouchard DR, Ross R, Janssen I. Coffee, tea and their additives: association with BMI and waist circumference. Obes Facts. 2010;3:345–52.
43. Basu A, Sanchez K, Leyva MJ, Wu M, Betts NM, Aston CE, et al. Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome. J Am Coll Nutr. 2010;29:31–40.
44. Brown AL, Lane J, Coverly J, Stocks J, Jackson S, Stephen A, et al. Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial. Br J Nutr. 2009;101:886–94.
