Un meta-análisis de consumo de café y té, y el riesgo de glioma en los adultos

27-04-2017

El café contiene muchos compuestos, incluyendo antioxidantes, que podrían prevenir el cáncer, y el café ha sido relacionado con una baja incidencia de cáncer en varios lugares. El té también es rico en antioxidantes, principalmente polifenoles. Para proporcionar una estimación cuantitativa total sobre la relación entre el café, el consumo de té y glioma este estudio combinó todos los datos publicados, a través de un acercamiento meta-analítico. Se realizó una búsqueda de bibliografía durante septiembre de 2012, en las bases de datos PubMed y Embase para identificar estudios observacionales que proporcionan estimaciones cuantitativas en este aspecto. Las estimaciones de los riesgos relativos (RR) acumulado y los intervalos de confianza del 95 % (IC) fueron calculados usando modelos de efectos arbitrarios. Entre los resultados se encontraron seis estudios (cuatro cohortes y dos estudios de casos y controles) disponibles para el meta-análisis, para un total de aproximadamente 2100 casos. El RRs y el IC 95 % de glioma para consumidores contra no consumidores/consumidores ocasionales fue 0.96 (IC 95 %: 0.81-1.13) para el café y 0.86 (IC 95 %: 0.78-0.94) para el té, sin heterogeneidad entre estudios. Cuando se comparó la categoría más alta vs la categoría más baja de consumo, el RR era 1.01 (IC 95 %: 0.83-1.22) para el café, 0.88 (IC 95 %: 0.69-1.12) para el té, y 0.75 (IC 95 %: 0.54-1.05) para el café más el té. En conclusión, este meta-análisis, aunque basado en pocos estudios, sugiere una falta de asociación entre la ingesta de café y el riesgo de glioma, y una tendencia, si existe alguna, de riesgo inferior para el bebedor de té y bebedor de café más y té.

Malerba S, Galeone C, Pelucchi C, Turati F, Hashibe M, La Vecchia C, Tavani A. A meta-analysis of coffee and tea consumption and the risk of glioma in adults. Canc Causes Contr 2013, 24: 267-276.

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